Data & AI Architect
Knowledge Graph engineer, agentic AI architect, and biomedical technologist building intelligence systems where science meets technology.
Portfolio
Thembelihle Gumede
Scientist & graph thinker
I'm a Data Scientist & AI Consultant with five years delivering end-to-end AI solutions — and over a decade as a Biomedical Technologist in Clinical Pathology. I pair deep technical skill with real clinical domain expertise, a rare combination for building AI that works in regulated, high-stakes environments.
I specialise in Knowledge Graph engineering with Neo4j and agentic AI — multi-agent planner-executor architectures and persistent memory systems, shipped in production for bioeconomy and clinical research.
I've managed laboratory operations, led HIV/STI/vaccine trials, and founded health ventures including Nguni Care and Biocollaborator.
5+
Years in Data & AI
10+
Years Clinical Pathology
R6.5M
Documented Savings
8
Certifications
Work that ships
P/01 — Analytics · Fraud Forensics
Funeral Assurance Analytics
Enterprise full-stack platform for KZN funeral assurance. Server-side Gemini generates and explains SQLite transactions across policy, claim and premium books, with D3 fraud-graph forensics and Neo4j collusion detection.
TypeScript · Neo4j · D3↗
P/02 — Knowledge Graph · Biomed
Biomedical Disease Mechanism KG
Heterogeneous knowledge graph linking disease mechanisms, drug targets, and biochemical pathway discoveries — built for graph-native biomedical reasoning and target identification.
Neo4j · Cypher · Ontology↗
P/03 — Clinical · EDC Automation
eCRF AutoBuilder — StitchEDC
Automated clinical metadata compiler that ingests unstructured trial protocols and outputs compliant study setups, mapping raw constraints into a formal 21-definition canonical schema.
Python · EDC · Schema↗
P/04 — Healthtech · Claims AI
Discovery Health Flywheel AI
Unified claims automation platform where intelligent claims savings are reinvested into proactive member health interventions — closing the loop between cost reduction and preventive care.
Healthtech · AI↗
Neo4jCypherGraphRAGPythonTensorFlowAgentic AITypeScriptReactD3.jsFastAPIPostgreSQLPL/pgSQLSparkAirflowPower BIGemini APIREDCapISO 15189AWSOracle OCI
Neo4jCypherGraphRAGPythonTensorFlowAgentic AITypeScriptReactD3.jsFastAPIPostgreSQLPL/pgSQLSparkAirflowPower BIGemini APIREDCapISO 15189AWSOracle OCI
What I build
01
Knowledge Graph Eng.
End-to-end Neo4j architecture — data modelling to production. GraphRAG integration for connecting siloed health, research, or enterprise data.
02
Agentic AI Systems
Autonomous multi-agent architectures, planner-executor workflows, and agentic memory. AI that reasons, persists, and acts across sessions.
03
Data Science & Analytics
EDA, predictive modelling, forecasting, and dashboards. From churn to resource planning — raw data into actionable intelligence.
04
Clinical Data Systems
Pipelines, QMS, and compliance for clinical trials and research labs. ISO 15189, GCLP, GCP, REDCap, Medidata.
05
AI Product Development
Prototype to production: computer vision, automation, AI health apps. Nguni Care reached 2,000+ users, Top 20 Africa Health 2024.
06
Community & Speaking
Workshops and capacity building on graph databases, GraphRAG, and AI for African organisations. Keynote and panel experience.
A decade at the edge
2026
Community Lead, Southern Africa @ Neo4j
Growing the graph database ecosystem across Southern Africa. Integrating GraphRAG and Knowledge Graphs into GenAI workflows. Speaker at Data & AI Community Day Durban.
2023
Founder & Data/AI Consultant @ TG Data Services
End-to-end AI across clinical research and bioeconomy. BioNexus AMR tracer Knowledge Graph; Project Continuum agentic memory system; production ML Ops.
2025
Research Laboratory Manager @ DTHF
Clinical study lab ops and compliance (SANAS, ISO 15189, GCLP). Achieved 30% efficiency increase, 25% audit-readiness improvement.
2022
Lab Lead Biomedical Technologist, Clinical Pathology @ Wits RHI
Led HIV, STI & vaccine trials. 100% regulatory compliance, 35% faster error resolution, R2.5M savings.
2020
Team Lead Biomedical Technologist, Clinical Pathology @ Anglo American
Established Saldanha laboratory from scratch — R4M annual savings, 20% productivity gain.
Tools & credentials
Graph & Knowledge Expert
Neo4jCypherAuraDBGraphRAGKnowledge GraphsAmazon NeptuneOntology Design
AI / ML & Agents Advanced
PythonTensorFlowLLM OrchestrationGemini APIMulti-Agent SystemsAgentic MemoryRAG PipelinesComputer Vision
Data & Backend Advanced
SQLPostgreSQLPL/pgSQLApache SparkFastAPIExpressAirflowdbtSupabase
Frontend & Viz Advanced
TypeScriptReactD3.jsPower BIViteTailwindHTMXTableau
Cloud & Infra Proficient
Oracle OCIAWSGoogle Cloud SQLGitHub ActionsNetlifyAnaconda
Clinical & Compliance Expert
REDCapMedidata RaveISO 15189PreclarusGCLPGCPPOPIABlockchain
Let's build
something
Open to freelance projects, consulting engagements, and senior remote roles in data, AI, and health technology.
+27 68 218 9500 — Durban, ZA — Open to Remote